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PDB ID: 1GFL F. Yang, L.G. Moss, G.N. Phillips Jr. The molecular structure of green fluorescent protein. Nat. Biotechnol. 14 pp. 1246 (1996)


BITC2003RFP
Request for Proposals
Posted March 2003

The Biomolecular Interaction Technologies Center (BITC) at the University of New Hampshire is soliciting research proposals for funding.

BITC is a National Science Foundation Industry/University Cooperative Research Center established to carry out research in coordination with pharmaceutical and biotechnology companies. For general information about BITC, its member companies, and a list of funded projects, go to the Web site: www.bitc.unh.edu.

Research proposals should deal with methods based preferably on first principles that can be used to quantitate the binding interaction between molecular species, specifically protein-protein interactions (including monoclonal antibodies), protein-nucleic acid interactions, small molecule drug-protein interactions and drug-lipid interactions. The development of new instruments or methods, or the refinement of existing equipment or techniques, will be considered. The objective should be the use of the instrument or method on a routine basis for either molecular screening or as an analytical technique in research relevant to drug discovery or development.

Areas of interest: 1) high-throughput binding assays; 2) more robust software for data acquisition analysis; and 3) improved methods for characterizing binding of membrane proteins. Technologies of particular interest to pharmaceutical researchers include but are not restricted to: atomic force microscopy, fluorescence spectroscopy, total internal reflection fluorescence spectroscopy, high-throughput calorimetry, surface plasmon resonance, coupled wavelength plasmon resonance, analytical electrophoresis, analytical ultracentrifugation, light scattering, circular dichroism, mass spectrometry, and nuclear magnetic resonance spectroscopy.

Researchers at academic institutions are eligible to apply. Proposals are accepted from outside the U.S.; however, the principal investigator must be a U.S. citizen and the research must be conducted within the U.S. Awards range from $15,000 to $100,000 per year; project duration is typically two years.        
                   
Submit a one-page preproposal via email as either an RTF or Word document, or as a PDF. Preproposals must include a description of the project, estimated cost, duration, and credentials of the principal investigator. Preproposal submission deadlines: May 1 and November 1. Email to: Dr. Thomas M. Laue, bitc.unh@unh.edu.

Preproposal
Selected
Invitation
Proposal

Receipt
Preproposal
To Submit Receipt
Funding
Dates
Review
Full Proposal
Dates
Decision
May 1
July
August
October 1
January
November 1
January
February
April 1
July


 


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