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Prior workshops: Reform School for
Ill-Behaved Proteins, July 2008 Allen Minton, National Institutes of Health “New light scattering method for detection and characterization of protein association in highly concentration solution” Jun Liu, Genentech, Inc. “Misbehaving Proteins – A Perspective from Biopharmaceutical Industry” C.Russ Middaugh,
“The Polyanion World and Ill-Behaved Proteins” Christopher J. Roberts, “What controls non-native aggregation of foldable Proteins? Competing views from polymer physics, colloid science, and protein chemistry” Yatin Gokarn, Amgen, Inc. “Good Proteins, Bad Environment: Role of Effective Charge in Governing Stability, Solubility & Rheology” Thomas Malia, Centocor, Inc. “Refolding of soluble and membrane proteins: methods and structural characterization” Characterizing the Physical Properties of Purified Antibodies, July 2007 Sandra Smith-Gill, National Cancer Institute, NIH “Thermodynamics and time-dependent stability of antibody-antigen complexes” Steve Shire, Genetech, Inc. “Monoclonal antibody viscosity and self-association: analytics and interpretation of results” Nick Pace, “Protein stability and solubility: contribution of net charge and individual amino acid side chains” Wayne Bolen, “Relating protein-osmolyte interactions to Protein solubility and stability” Eric Sundberg, “Energetic cooperativity in protein-protein interactions” Innovations in
Analytical Ultracentrifugation and Surface Plasmon
Resonance: Advanced Instruments and
Analysis Software, July 2004 Fluorescence detection optical system for the analytical ultracentrifuge: data acquisition and analysis, operating system and simulation software. Biacore’s surface plasmon resonance biosensor (3000): advance techniques and GPCR studies. Walter Stafford, David Myszka, Thomas Laue, Center to Advance Molecualr Itneraction Science Simon Cocklin, Kenneth Miller and Brian Lang, Biacore Fluorescence
Spectroscopy of Ligan Binding, July 2003 Joe Beechem, Molecular Probes: HTS assays Zygmunt Gryczynski, Center for fluorescence Spectrosocpy: General principles, polarization, new developments Nancy Thompson, U. James Foley, Rowland Institute, Harvard: Fluorescent dyes Curve Fitting and
Data Analysis, July 2002 Norma Greenfied, UNJMD, circular dichroism Tom Laue, CAMIS, sedimentation equilibrium Ernst Linder, UNH, generalized curve fitting David Myszka, U. Utah, surface plasmon resonance John Philo, Alliance Protein, sedimentation velocity
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